NURS 8310/ NURS 8310C:Week 3: Analytic Epidemiology Designs Essay Assignment Paper

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NURS 8310/ NURS 8310C:Week 3: Analytic Epidemiology Designs Essay Assignment Paper

NURS 8310/ NURS 8310F/ NURS 8310M/ NURS 8310A/ NURS 8310C:Week 3: Analytic Epidemiology Designs: Observational

Consider for a moment the great strides made in treating breast cancer, or as noted last week, the change in life expectancy for patients with HIV/AIDS. These strides toward improving health outcomes are a result of research; research has helped health care professionals and others better understand disease and, therefore, offer more effective treatment.

In Week 2, you explored descriptive epidemiological studies, examining the distribution of disease in terms of person, place, and time. This week you will begin looking at analytic epidemiology designs that focus on the association between an exposure to a risk factor (e.g., radiation, cigarette smoke, poor diet) and the resulting health outcomes. You will examine observational studies in particular, and you will consider how and why this approach could be appropriate for a specific health problem and population. In addition, you will select a significant population health problem of interest to you in preparation for Major Assessment 7.

NURS 8310/ NURS 8310C:Week 3: Analytic Epidemiology Designs Essay Assignment Paper

Learning Objectives

Students will:

• Analyze observational study designs used in analytic epidemiology
• Evaluate the application of observational studies for improving population health status
• Characterize a significant population health problem

Learning Resources

Note: To access this week’s required library resources, please click on the link to the Course Readings List, found in the Course Materials section of your Syllabus.

Required Readings

Friis, R. H., & Sellers, T. A. (2014). Epidemiology for public health practice (5th ed.). Sudbury, MA: Jones & Bartlett.

• • Chapter 6, “Study Designs: Ecologic, Cross-Sectional, Case Control”
  • Chapter 7, “Study Designs: Cohort Studies”

 

Chapter 6 presents an overview of analytic study designs used in epidemiology, differentiating between experimental studies (which will be addressed next week) and observational studies (the focus of this week). In the chapter, the authors address three varieties of observational studies—ecological, cross-sectional, and case control. Chapter 7 addresses cohort studies, another form of observational design.

Doll, R., & Hill, A. B. (1999). Smoking and carcinoma of the lung. Bulletin of the World Health Organization, 77(1), 84–93.

.This landmark case-control study established the relationship between smoking and lung cancer.

Framingham Heart Study. (2018). Epidemiological background and design: The Framingham study. Retrieved from https://www.framinghamheartstudy.org/fhs-about/history/epidemiological-background/

The Framingham Heart Study is one of the first and largest cohort studies that measured the distribution of suspected risk factors in a large population and then tracked the development of heart disease in that cohort.

Papathanasiou, A. A., & Zintzaras, E. (2010). Assessing the quality of reporting of observational studies in cancer. Annals of Epidemiology, 20(1), 67–73.

In this article, the authors assess the quality of reporting of observational cancer studies, noting opportunities for improvement.

Von Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., & Vandenbroucke, J. P. (2007). Strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies. Annals of Internal Medicine, 147(8), 573–577.

A consortium of scientists and medical researchers created a checklist of 22 recommended items that should be included in reports about three common observational study designs: case-control, cohort, and cross-sectional studies. This collaborative effort is an important step toward the goal of improving the quality, credibility, and generalizability of analytical research.

Healthy People 2020. (2011). Topics & objectives index. Retrieved from http://healthypeople.gov/2020/topicsobjectives2020/default.aspx

Healthy People 2020 focuses on improving population health locally and nationally. Review the topics and objectives of Healthy People 2020 as you prepare for Assignment 2.

Required Media

Laureate Education, Inc. (Executive Producer). (2012). Epidemiology and population health: Observational studies[Video file]. Baltimore, MD: Author.

Note: The approximate length of this media piece is 9 minutes.

In this week’s program, the presenters discuss observational studies as a means of establishing an association between an exposure or risk factor and a disease outcome. Two types of observational designs are featured: cohort and case control studies

Optional Resources

The following ERIC notebook guides present information in a reader-friendly study guide format.

Ibrahim, M., Alexander, L., Shy, C., & Farr, S. (1999). Cohort studies. ERIC Notebook, 3, 1–4. Retrieved from http://cphp.sph.unc.edu/trainingpackages/ERIC/eric_notebook_3.pdf

Ibrahim, M., Alexander, L., Shy, C., & Farr, S. (1999). Incidence measures in cohort studies. ERIC Notebook, 4, 1–4. Retrieved from http://cphp.sph.unc.edu/trainingpackages/ERIC/eric_notebook_4.pdf

Ibrahim, M., Alexander, L., Shy, C., & Farr, S. (1999). Case-control studies. ERIC Notebook, 5, 1–4. Retrieved from http://cphp.sph.unc.edu/trainingpackages/ERIC/eric_notebook_5.pdf

Ibrahim, M., Alexander, L., Shy, C., & Farr, S. (1999). Cross-sectional studies. ERIC Notebook, 7, 1–4. Retrieved from http://cphp.sph.unc.edu/trainingpackages/ERIC/eric_notebook_7.pdf

Ibrahim, M., Alexander, L., Shy, C., & Farr, S. (2000). Ecologic studies. ERIC Notebook, 12, 1–4. Retrieved from http://cphp.sph.unc.edu/trainingpackages/ERIC/eric_notebook_12.pdf

NURS 8310/ NURS 8310C:Week 3: Analytic Epidemiology Designs Essay Assignment Paper

Discussion: Observational Study Designs

A clinical pediatric nurse has noticed a rise in childhood cancer diagnoses among the Hispanic population served by the local clinic. The nurse is concerned about this increase in cancer incidence in the patient population and turns to the literature to explore current research on this topic. The nurse finds through the reading that there appears to be an association between parental smoking and childhood cancer and wonders if this could be the cause of the rise in cases.

This type of suspected association between a risk factor (exposure) and a particular outcome (childhood cancer) can be evaluated using an observational study design. This week, you were introduced to observational study designs used in epidemiology. For this Discussion, you will identify an epidemiologic association of interest (e.g., smoking and lung cancer, obesity and heart disease, hormone replacement/modification therapy and breast cancer) and determine an appropriate observational study design for exploring that association.

To prepare:

• Review the different types of observational study designs presented in the Learning Resources: ecologic, cross-sectional, case-control, and cohort.
• Carefully examine the characteristics, strengths, and limitations of each design.
• Consider an association between a risk factor and a particular health outcome that is of interest to you. Then, select the observational study design you think would be the most appropriate for exploring this association.
• Consider how using observational study designs can lead to improvements in population health.

By Day 3

Post a cohesive response that addresses the following:

• Identify the association between the risk factor and health outcome you selected, and suggest which observational study design you feel is most appropriate for examining that association.
• Support your selection of the observational design, noting its strengths and limitations for addressing the health problem.
• What might you be able to learn by using your selected study design that might lead to improvements in population health? Support your response with evidence from the literature.

Read a selection of your colleagues’ responses.

By Day 6

Respond to at least three of your colleagues in one or more of the following ways:

• Suggest a different study design that would be appropriate for your colleague’s health problem.
• Ask a probing question, substantiated with additional background information, evidence, or research.
• Share an insight from having read your colleagues’ postings, synthesizing the information to provide new perspectives.
• Offer and support an alternative perspective using readings from the classroom or from your own research in the Walden Library.
• Validate an idea with your own experience and additional research.
• Make a suggestion based on additional evidence drawn from readings or after synthesizing multiple postings.
• Expand on your colleagues’ postings by providing additional insights or contrasting perspectives based on readings and evidence.

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