Paternal Grandfather and A Grandson  Essay Assignment Paper

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 Paternal Grandfather and A Grandson  Essay Assignment Paper



This project evaluates your understanding of the unique inheritance of autosomal DNA, the limitations of at DNA testing, and how at DNA is transmitted from one generation to the next.

The following is a comparison of the DNA of a paternal grandfather and a grandson on chromosome 1, where gray indicates the chromosome and brown indicates the shared segments of DNA of 1 line representing Chromosome 1. Within the line segment, it is grey, brown, grey, brown, grey.

On the basis of your understanding of autosomal DNA and this comparison, answer the following questions:

  1. Since this comparison is of a paternal grandfather and a grandson, it represents a single recombination. At least how many recombination events had to occur in order to observe this pattern?
  2. Based on the above comparison alone, can you determine the segments of DNA on chromosome 1 that the grandson received from his maternal grandmother? Why or why not?
  3. Let’s follow the same chromosome through to the next generation, to the grandson’s son, and compare it to the same paternal grandfather (now a great-grandfather). Could the comparison of the great-grandfather and great-grandson look like the result below? Why or why not?

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